Scientist II, T Cell Tolerance

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas – immunology, oncology, neuroscience, and eye care – and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on X, Facebook, Instagram, YouTube, LinkedIn and Tik Tok.

The Immunology Discovery Department at AbbVie is seeking a highly motivated and innovative candidate for the role of Scientist II within the Immune Tolerance Therapeutics Discovery team based in Cambridge, MA. The successful candidate for this position will be a technical expert in their field and will play a critical role in supporting various in vivo and in vitro preclinical studies with emphasis on mechanisms of tissue-resident T cells in immune tolerance and autoimmune disease. They will be required to work independently on a variety of in vivo animal models to better understand TRM cell biology and characterize and evaluate biological compounds. This individual will have a strong background in scientific research, with the ability to organize, analyze and interpret results, come forward with recommendations including presenting findings to senior personnel or in team meetings. Experience in primary immune cell cultures and functional assays as well as processing human and rodent tissues is required. Experience with flow cytometry as well as other laboratory techniques is an advantage. Working knowledge of immunology and/or pharmacology is a plus. The successful candidate will be collaborating extensively with other Research Associates and Scientists in a multidisciplinary team, while taking personal responsibility for the success of assigned tasks and projects.

Key Responsibilities:

• Independently design, plan, and execute in vivo and ex vivo studies and analyze results to answer scientific questions.
• Develop and optimize experimental protocols and methodologies.
• Ensure reproducibility and reliability of experimental results.
• Set goals and meet experimental timelines and execute a strategy in alignment with the goals and broad key scientific objectives for the research.
• Demonstrate creative ‘out of the box’ thinking to solve problems and modify experimental plans when required to achieve project goals.
• Understand the broad objectives of the project as well as their role in achieving those objectives.
• Make significant contributions to project teams through lab-based, or other work environment activities.
• Analyze and interpret experimental data using statistical methods, author protocols and scientific reports, and present data to multidisciplinary teams and to management.
• Contribute to writing and conceptual framework of publications, patents, and presentations.
• Effectively organize and present program updates and research strategies to functional leaders as well as potential and existing partners.
• Build strong relationships with cross-functional team members to accomplish the goals and requirements of the organization.
• Understand and adhere to corporate standards regarding code of conduct, safety, appropriate handling of materials, controlled drug, and animal care where applicable.
• Grasp abstract ideas, learn quickly, and pivot as needed.
• Learn, understand, and become proficient at new experimental techniques, and act as resource and mentor for junior scientists.
• Identify and propose innovative solutions to scientific problems.
• Stay current with scientific literature and advancements in the field.

Qualifications:

• BS or equivalent education with typically 7 or more years of experience or MS or equivalent education with typically 5 or more years of experience.
• Expertise in human and rodent tissue processing.
• Proficiency with small animal handling, dosing of molecules through a variety of different routes and tissue harvest is required.
• Demonstrated track record of scientific research and publications.
• Proficiency in pharmacological assays, focusing on in vivo pharmacology.
• Direct experience with peripheral animal models and measurements.
• Highly motivated, hands-on experimentalist who thrives in a collaborative, multidisciplinary environment.
• Demonstrated ability to independently design, execute, and interpret critical experiments.
• Ability to scientifically lead programs, learn new technologies, and train associates.
• Meticulous attention to detail and diligence in record keeping, exhibits excellent oral and written communication.
• Ability to critically analyze data and lead teams to solve problems and make best strategic decisions.
• Highly collaborative, team-oriented, and considerate of the needs of others.
• Strong interpersonal skills and ability to collaborate effectively with cross functional partners.
• Help create an inclusive environment where diverse ideas, viewpoints and backgrounds are valued.
• Excellent written and communication skills.
• Computer skills: a working knowledge of MS-Office (Excel, Word, PowerPoint) is required.
• Strong analytic skills and proficiency in graphing software (e.g., GraphPad prism) and statistical analyses is required.

Preferred Experience:

• Working knowledge of immunology and animal anatomy is a plus.
• Experience contributing to technical reports and regulatory documents is a plus.
• Experience with spectral flow cytometry, as well as other laboratory techniques is a plus.

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: ​​

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• The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.​​

  
  

• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.​​

  
  

• This job is eligible to participate in our short-term incentive programs. ​​

  
  

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Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law. 

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives, serving our community and embracing diversity and inclusion.  It is AbbVie’s policy to employ qualified persons of the greatest ability without discrimination against any employee or applicant for employment because of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information, gender identity or expression, sexual orientation, marital status, status as a protected veteran, or any other legally protected group status.

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