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Job Description

Career CategoryQualityJob Description

Join Amgen’s Mission of Serving Patients


At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.


Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.


Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.


What you will do


Let’s do this. Let’s change the world. In this vital role you will lead the execution of complex or novel assignments requiring strategic planning and development of new and/or improved validation techniques, deviations, and procedures. In this position you will supervise validation activities through internal audits and conduct risk assessments to identify the need for requalification and establish policies for computer system re-validation.


This individual will actively participate during all phases of qualification/validation of computerized systems: evaluate projects; provide guidance and technical information to others (lead qualification/validation activities); determine and establish requirements for qualification/validation of each individual system/equipment; formulate independent decisions related to qualification/verification activities.


Responsibilities


Serve as Owner or QA Contact for Minor and Major Deviations. Review validation/qualification packages of computerized systems for completeness and accuracy, sound rationale, Regulatory expectations, compliance with validation policies and procedures, and accurate data analysis. Compare results against acceptance criteria and work with appropriate departments to resolve exceptions and deviations. Bring critical exceptions or deviations to management’s attention and initiate and enforce necessary improvements and corrections to established systems and processes. Initiate, implement, and track completion of Change Control and deviation requests related to computer systems. Participation and support of regulatory inspections.


  • Initiate and own QA Deviations (Major, Minor) as needed


  • Serve as QA contact for Major, Minor deviations


  • Serve as Owner or QA contact for CAPA and Effectiveness Verification (EV) records


  • Serve as Quality approver for problem records in ServiceNow


  • Review and approve Requirement Specifications, Design Specifications, Testing Protocols, Validation Plans, Summary Reports, and Requirement Traceability Matrices


  • Review and approve operational and administrative SOPs and Work Instructions


  • Review and approve Change Controls (QA Contact role for CCMS and ServiceNow changes)


  • Review and approve Data Integrity Assessments


  • Review and approve System Life Cycle Documents (i.e. test protocols) before use in production.


  • Applies analytical skills to evaluate and interpret complex situations/problems using multiple sources of information (e.g., Qualitative information, Quantitative research, Trend data)


  • Anticipates and prevents potential problems


  • May be responsible for specific GxP Computerized Systems programs and/or projects


  • Independently develops solutions that are thorough, practical and consistent with functional objectives


What we expect of you


We are all different, yet we all use our unique contributions to serve patients.


Basic Qualifications:


  • Master’s degree and 4 to 6 years of Computer Science or related field and 5+ years of Software and Systems Quality assurance experience OR


  • Bachelor’s degree and 6 to 8 years of Computer Science or related field and 5+ years of Software and Systems Quality assurance experience OR


  • Diploma and 10 to 12 years of Computer Science or related field and 5+ years of Software and Systems Quality assurance experience


Preferred Qualifications:


  • Experience owning Major and Minor Deviations


  • Technical knowledge of IS systems such as LIMS, CDOCS, SAP, Maximo


  • Ability to interpret and apply GxP (GMP, GLP, GCP, GPvP, GDP)


  • Broad technical knowledge within own specialty area


  • Knowledge of industry and business principles


  • Demonstrated problem solving abilities


  • Contributes to work group/team by ensuring quality of tasks/ services provided by self and others


  • Provides training and guidance to others


  • Extends capabilities by working closely with senior staff/ experts within and outside the internal organization


  • Experience serving as QA Contact for Major and Minor Deviations


  • Experience in GxP computerized systems validation


What you can expect of us


As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.


In addition to the base salary, Amgen offers competitive and comprehensive Total Rewards Plans that are aligned with local industry standards.


Apply now


for a career that defies imagination


Objects in your future are closer than they appear. Join us.


careers.amgen.com


As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.


Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.


We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.


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