Senior Scientist II, Biologics In Vitro Technologies

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas – immunology, oncology, neuroscience, and eye care – and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on X, Facebook, Instagram, YouTube, LinkedIn and Tik Tok.

The Biologics Discovery Sciences Group at AbbVie is seeking an accomplished scientist who will make substantial contributions to the conception, execution, and communication of antibody discovery strategies in a highly collaborative environment.  A primary responsibility will be to develop and execute research strategies to enable the discovery and development of therapeutic antibodies for AbbVie’s core therapeutics areas. They will be responsible for the design and execution of in vitro display technologies for lead antibody identification/optimization.  In addition, it is expected that the candidate will utilize their expertise to generate internal and external collaborations as necessary to further program goals. The successful candidate will be responsible for driving antibody discovery programs within a multidisciplinary research group in an exciting, fast-paced team environment.

Key Responsibilities:

• Contribute to the conception, execution and communication of antibody discovery strategies in a highly collaborative environment.
• Develop and execute research strategies to enable the discovery and development of therapeutic antibodies and for AbbVie’s core therapeutics areas.
• Design and execution of in vitro display technologies for lead antibody identification/optimization and collaborating to generate stage-gate appropriate in vitro / cellular / in vivo data packages supporting PoC.
• Leverage expertise to develop and implement research to gain a detailed mechanistic understanding of the molecular pharmacology of therapeutic molecules.
• Ensure consistency and quality of technical reports.
• Provide project update, analysis and advice to cross-functional teams and senior management.
• Present original work internally across departments and at internal and external scientific conferences.

Qualifications:

• PhD, MS, or BS degree in Biochemistry, Biochemical engineering or related disciplines with typically 4+ (PhD), 10+ (MS), or 12+ (BS) years of experience
• Hands-on experience with in vitro antibody discovery display technologies (e.g., phage, yeast, mammalian)
• Antibody/antibody fragment library design and construction
• Strong molecular biology skills
• Familiarity with sequence analysis tools (Geneious, Sequencher)
• Experience with flow cytometry
• Deep understanding of antibody structure and function
• Experience in antibody engineering and optimization (e.g., humanization, Fc optimization)
• Ability to explore and develop new approaches to further advance innovative biologics discovery
• Highly developed leadership and communication skills
• Keen ability to engage internal and external scientific leaders in collaborative research
• Excellent organization skills and the ability to manage multiple projects simultaneously
• Work in a collaborative environment with functional and therapeutic areas
• Adapt to rapid changes in project priorities and timelines

Key AbbVie Competencies:

• Builds strong relationships with peers and cross functionally with partners outside of the team to enable higher performance.
• Learns fast, grasps the “essence” and can change the course quickly where indicated.
• Raises the bar and is never satisfied with the status quo.
• Creates a learning environment, open to suggestions and experimentation for improvement.
• Embraces the ideas of others, nurtures innovation and manages innovation to reality.

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: ​

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• The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.​

  
  

• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.​

  
  

• This job is eligible to participate in our short-term incentive programs. ​

  
  

• This job is eligible to participate in our long-term incentive programs​

  
  

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Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law. 

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives, serving our community and embracing diversity and inclusion.  It is AbbVie’s policy to employ qualified persons of the greatest ability without discrimination against any employee or applicant for employment because of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information, gender identity or expression, sexual orientation, marital status, status as a protected veteran, or any other legally protected group status.

US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html 

US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:

https://www.abbvie.com/join-us/reasonable-accommodations.html