Principal Research Scientist I, Early Exploratory Target Generation

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas – immunology, oncology, neuroscience, and eye care – and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on X, Facebook, Instagram, YouTube, LinkedIn and Tik Tok.

Are you a visionary scientist with a passion for discovering groundbreaking biotherapeutic solutions? Do you find excitement in exploring the forefront of scientific innovation? AbbVie's Discovery Biotherapeutics and Genetic Medicine (BGM) team in Cambridge, MA, invites you to join us as a Principal Research Scientist I in the Protein Sciences group. Your work will help develop transformative ideas driving our immunology and neuroscience therapeutic areas towards the clinic.

Role Overview:

As a Principal Research Scientist, you’ll be at the helm of early exploratory target selection, offering strategic guidance in antigen generation, production, and procurement. In this leadership role, your expertise will foster scientific excellence and collaboration while pioneering novel techniques in protein target design and expression. Join us to lead the charge in making meaningful scientific advancements.

Key Responsibilities:

• Spearhead activities in the early exploratory stages of target selection within the immunology and neuroscience therapeutic areas

• Innovatively design and produce soluble and membrane protein targets with enhanced stability for functional studies and antibody discovery
• Collaborate with protein vendors and Contract Research Organizations (CROs) to secure and produce high-quality antigens
• Foster strong cross-functional collaborations with therapeutic area partners to promote the generation of innovative ideas and solutions that support organizational objectives.
• Clearly and effectively explain research findings and strategies through scientific reports, publications, and presentations tailored for diverse audiences.
• Contribute to scientific excellence through dedication to multiple projects in a fast-paced, multi-disciplinary environment.
• Cultivate innovative problem-solving by generating original technical ideas and responding to scientific, regulatory, and competitive developments.
• Mentor and empower others to publish and present research externally, evaluating their performance and professional development.

Qualifications:

• BS with typically 14+ years, MS with typically 12+ years, or PhD with typically 6+ years of experience in Biochemistry, Molecular and Cell Biology or related field.
• Extensive experience in early-stage biotherapeutic discovery, particularly within neuroscience and immunology therapeutic areas.
• Proficient in expression and purification from various host expression systems.
• Proven research excellence demonstrated through a strong track record of publications, presentations and scientific achievements.
• Demonstrated ability to lead cross-functional research teams, manage projects, and effectively communicate with stakeholders.
• Expertise in navigating and managing relationships with different protein vendors and CROs, ensuring alignment with project goals and timelines.
• Experience working with multispecific biologics is a plus.

Key Leadership Competencies:

• Learns fast, grasps the "essence" and can change course quickly where indicated
• Raises the bar and is never satisfied with the status quo
• Creates a learning environment, open to suggestions and experimentation for improvement
• Embraces the ideas of others, nurtures innovation and manages innovation to reality

AbbVie is committed to fostering an inclusive and diverse work environment. Be part of our team that is curious, open-minded, and ready to tackle the biotherapeutic challenges of tomorrow!

Apply today to embark on a rewarding journey that contributes to making a real difference in patients' lives. Discover your potential with AbbVie.

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: ​

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• The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.​

  
  

• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.​

  
  

• This job is eligible to participate in our short-term incentive programs. ​

  
  

• This job is eligible to participate in our long-term incentive programs​

  
  

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Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law. ​

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